diff --git a/tests/run-make/remap-path-prefix-doctest-panic/rmake.rs b/tests/run-make/remap-path-prefix-doctest-panic/rmake.rs
new file mode 100644
index 0000000000000..058f62e980fef
--- /dev/null
+++ b/tests/run-make/remap-path-prefix-doctest-panic/rmake.rs
@@ -0,0 +1,55 @@
+// Checks that the location printed by a panicking doctest is remapped
+// according to `--remap-path-scope`.
+//
+// Only the lines between the start of the stack backtrace and the end are
+// are inspected, so timings, temp dirs and backtraces can't leak into the check.
+
+//@ ignore-cross-compile
+//@ ignore-windows
+
+use run_make_support::assertion_helpers::{assert_contains, assert_not_contains};
+use run_make_support::rustdoc;
+
+/// Runs the failing doctest and returns stdout.
+fn panic_file(scope: Option<&str>) -> String {
+    let mut cmd = rustdoc();
+    cmd.input("src/doctest.rs")
+        .arg("--test")
+        .arg("--remap-path-prefix=src=/REMAPPED")
+        .arg("-Cdebuginfo=1")
+        .arg("--edition=2015")
+        .env("RUST_BACKTRACE", "1");
+
+    if let Some(scope) = scope {
+        cmd.arg(format!("--remap-path-scope={scope}")).arg("-Zunstable-options");
+    }
+
+    let out = cmd.run_fail();
+    out.assert_stdout_contains("explicit panic");
+
+    let stdout = out.stdout_utf8();
+    let section: Vec<&str> = stdout
+        .lines()
+        .skip_while(|l| l.trim() != "stack backtrace:")
+        .skip(1)
+        .take_while(|l| l.trim() != "failures:")
+        .collect();
+
+    assert!(!section.is_empty(), "no backtrace found in output:\n{stdout}");
+    section.join("\n")
+}
+
+fn main() {
+    // Check that with debuginfo (and related) we get the remapped path
+    for scope in [Some("debuginfo"), Some("object"), Some("all"), None] {
+        let stdout = panic_file(scope);
+        assert_contains(&stdout, "/REMAPPED/doctest.rs");
+        assert_not_contains(&stdout, "src/doctest.rs");
+    }
+
+    for scope in ["diagnostics", "documentation", "macro"] {
+        let stdout = panic_file(Some(scope));
+        assert_contains(&stdout, "src/doctest.rs");
+        assert_not_contains(&stdout, "/REMAPPED/doctest.rs");
+    }
+}
diff --git a/tests/run-make/remap-path-prefix-doctest-panic/src/doctest.rs b/tests/run-make/remap-path-prefix-doctest-panic/src/doctest.rs
new file mode 100644
index 0000000000000..2160cc21f6b42
--- /dev/null
+++ b/tests/run-make/remap-path-prefix-doctest-panic/src/doctest.rs
@@ -0,0 +1,4 @@
+/// ```
+/// panic!()
+/// ```
+pub fn f() {}