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Bound JN4-GD17 graph output, competition signs and causal assays #1340

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@realmarcin

Source-Based Graph Findings

CommunityMech:000180, Clostridium_Thermoanaerobacterium_JN4_GD17_Cellulosic_Biofuel_Coculture.yaml.

Primary 2019 main body, Methods, Results, Discussion and captions read: https://doi.org/10.3389/fmicb.2019.02035. PMID:27538932 is abstract-only here.

  • Product enhancement is currently encoded as directed cross-feeding of cellulose. Represent the measured consortium output separately from the proposed soluble-sugar supply.
  • Preserve the strong evidence for GD17 substrate conversion and JN4 growth suppression, but the COMPETITION enum requires reciprocal harm, not merely resource competition.
  • Growth estimates combine protein, optical-density calibration and genomic composition, not direct viable counts. Preserve the glucose/transcription and stimulant controls while qualifying mediator attribution.
  • Account for all three nodes and both arrows; distinguish improved products from cellulose utilization and from the supplemented rebalancing arm.

No new structure is proposed. Guarded graph-only repair, append-only history, complete decisions and source-based self-adversarial review required. Unrelated metadata is a separate followup.

Deduplication: all 678 prior issue titles/bodies searched; relevant #639, #529, #749, #752 reviewed. Ignored/hidden local reports, history, research and tests included. No duplicate exact graph finding in that scope; issue comments not exhaustively searched.

Activity

  1. realmarcin commented on Oct 6, 2026

    @realmarcin
    ContributorAuthor

    Addressed in #1346 at d71b3800c819fff8b4c5a32bb99d0f68e5ca85c3. Exact-head source-based self-adversarial review: #1346 (review). All 30 local gates and actual post-commit docs-current passed; 270 passed in 237.82s (0:03:57); 87 MATCH snippets, zero other classes; 3 passed in 2.14s; 55 unrelated raw blocks and seven caches byte-preserved. See committed batch22 decision/adversarial/validation records for assay bounds and full node/arrow accounting. This issue remains open until protected main merge; #1343 is separate non-graph work.

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