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EcoFAB SynCom17 graph: separate treatment effects from trait hypotheses and sterile-plant experiments #1424

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@realmarcin

EcoFAB_Ring_Trial_SynCom17.yaml, PMID:40920748, doi:10.1126/sciadv.adg7888.

Remove Nitrogen-Status EcoFAB Root Exudation from this graph: that separate study used sterile plants and individual bacterial bioassays, not SynCom17 co-inoculation. Retain the three whole-treatment outcome arrows. The OAS925 trait-to-dominance arrow is HYPOTHESIZED: separate isolate motility/biofilm/root-colonization assays and genomic annotations do not isolate a dominance mechanism. The dominance-to-metabolome arrow is unsupported mediation: bulk profiles allow root/microbial production, uptake and extracellular enzyme activity. Remove that arrow, categorical competition, facilitation and cross-feeding annotations, and unsupported symbiotic-process terms. Preserve directly measured outcomes and canonical participants, representing the OAS925 trait node as source-only PAIRWISE, not a self-edge. No new nodes or arrows needed.

Deduplication: 748 all-state issue titles/bodies and ignored/hidden-inclusive local review, research, history, tests, scripts and workflow files. Relevant #1264, #826, #827, #830, #365 and #442 read; no exact duplicate within that scope. Not every issue comment searched. Primary cached main-body texts reviewed, not visual figures, raw data or separate supplements.

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  1. realmarcin commented on Oct 6, 2026

    @realmarcin
    ContributorAuthor

    Graph defect addressed in #1430 at a691e1d. Exact-head self-adversarial COMMENT: #1430 (review). 392 passed in 179.44s (0:02:59); actual post-commit docs-current passed. Includes removal of the HMO part/whole summary arrow as well as the EcoFAB mediation arrow. Close only after protected main merge. Non-graph #1427/#1428/#1429 remain open.

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