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Arg-Met graph: scope obligate exchange and fluorescence noise to the tested reporter conditions #1431
Keep both genotype-specific reciprocal exchange nodes and canonical NCBITaxon:511145 labels, without collapsing the two strains. Obligation holds under the tested amino-acid limitation; supplementation changes the interaction. The endpoint is single-cell fluorescent-reporter coefficient of variation, not directly resolved intrinsic transcriptional noise or universal protein-expression noise. Remove GO:0044419 interspecies annotation for these same-species strains. Preserve zero arrows while a separate source-backed mechanism expansion is researched; do not claim the expansion complete after node qualification. Keep the Arg-Trp and BL21/environmental-isolate experiments out of this two-strain graph.
Deduplication: 754 all-state issue titles/bodies, plus ignored/hidden-inclusive local review/research/history/tests/scripts/workflow search. Relevant #1164, #373, #1120 and #1121 read; #373 reused. Not every issue comment searched. No exact duplicate of these new findings in that scope.
Existing-graph defect addressed in #1437 at a22f0f8. Exact-head self-adversarial COMMENT: #1437 (review). 399 passed in 179.40s (0:02:59); actual post-commit docs-current passed. Three VFA arrows removed and two qualified; Arg/Met expansion remains pending under #1436. Close only after protected main merge. Other follow-ups remain open.
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realmarcin commentedon Oct 6, 2026
Existing-graph defect addressed in #1437 at a22f0f8. Exact-head self-adversarial COMMENT: #1437 (review). 399 passed in 179.40s (0:02:59); actual post-commit docs-current passed. Three VFA arrows removed and two qualified; Arg/Met expansion remains pending under #1436. Close only after protected main merge. Other follow-ups remain open.