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GENIA graph: separate predicted complementarity, reported removal and compositional intervention #1466
Genome annotations and cross-platform agreement are computational hypotheses, not measured metabolite handoffs or established niche partitioning. The assembly-to-removal arrow overstates design as a demonstrated biological mediator. Better removal than the best monoculture is not mutualism. Separate-treatment figures (93.1% PFOS, 91.4% atrazine, 91.6% lignin) differ from the separately reported seven-day mixed-pollutant figures (87.1%, 84.7%, 88.9%). Full-length 16S DNA profiles do not establish viability, strain-resolved flux, or necessity of predicted hubs.
The main body does report a daily equal-ratio dilution/remixing comparison. This supports a bounded PARTIAL composition-management effect, not the existing claim that persistence of the full roster causally maintains a specific cross-feeding network. Retain at most that qualified existing dynamics-to-removal arrow; remove the design arrow and unsupported categories. Preserve source-reported observations without endorsing the article's internally conflicting mass balances: 37.1 micromolar PFOS x 17 x 19 gives about 12.0 mg/L total fluorine, not 64.08; Methods also mention PFOA/PFOS mixtures, so the denominator cannot be resolved by assuming PFOS alone. Atrazine concentration, nitrogen yield and colorimetric method descriptions also conflict.
Acceptance: bounded existing nodes and canonical participant lists, explicit evidence modalities, hypothesis/measurement caveats, exact renamed targets, focused gap, append-only history, regression tests and generated page. No new structure required. Full cached primary main body, Methods and captions read; no supplementary files, images or raw analytical data independently inspected. Preserve #812/#813/#817 fixes.
Deduplication covered 783 all-state issue titles/bodies and ignored/hidden-inclusive local reports, research, history, tests, scripts and workflows, including exact PMIDs/DOIs. All 17 matched issue bodies read, not all comments or PR reviews. No exact duplicate found within that scope. This is source-based self-adversarial review, not independent approval.
Correction addressed in #1470 at 22b5b12. Exact-head source-based self-adversarial COMMENT: #1470 (review). 440 passed in 203.92s (0:03:23); post-commit docs-current passed. Fucoidan retains 14 unchanged reference-CLI findings, not a clean pass. Close only after protected main merge.
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realmarcin commentedon Oct 6, 2026
Correction addressed in #1470 at 22b5b12. Exact-head source-based self-adversarial COMMENT: #1470 (review). 440 passed in 203.92s (0:03:23); post-commit docs-current passed. Fucoidan retains 14 unchanged reference-CLI findings, not a clean pass. Close only after protected main merge.