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Separate Ogataea growth rescue from inferred sulfur exchange and endpoint bias #1653
CommunityMech:000450; PMID42318495. Preserve measured complementation and controlled initial-ratio effects. Single-strain supplementation supports asymmetric nutrient requirements, not measured met10-to-str3 homocysteine flux; paper explicitly calls for tracer/metabolomics. Correct implication that every ratio grows well or necessarily increases met10 fraction. FY31/FY34 are population-tracking strains, not automatically all screening genotypes. Preserve1151 canonical strain identities,1149 medium conditions and1150 dangling-outcome removal. Full primary main text read. Close only after protected-main merge.
Dedup:933 all-state issue titles/bodies and25 ignored/hidden-inclusive local matched files (git/docs/site/reference-cache excluded); matching258/650/981/1149/1150/1151 read. No exhaustive PR-comment audit. Source-based self-adversarial review is not independent approval.
Addressed in #1659 at 5099a66; exact-head self-review:#1659 (review). 706 passed in 206.85s (0:03:26); post-commit docs-current passed. Every-node/every-arrow decisions and actual output digests committed. Not independent approval; close only after protected-main merge. Metadata #1658 remains unfinished; all four current reference gates passed.
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realmarcin commentedon Oct 7, 2026
Addressed in #1659 at 5099a66; exact-head self-review:#1659 (review). 706 passed in 206.85s (0:03:26); post-commit docs-current passed. Every-node/every-arrow decisions and actual output digests committed. Not independent approval; close only after protected-main merge. Metadata #1658 remains unfinished; all four current reference gates passed.