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449 changes: 94 additions & 355 deletions docs/communities/Dangl_SynComm_35.html

Large diffs are not rendered by default.

250 changes: 100 additions & 150 deletions docs/communities/Deepwater_Horizon_Deep_Sea_Oil_Plume_Succession.html

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171 changes: 117 additions & 54 deletions docs/communities/Defined_Multispecies_Enamel_Caries_Model.html
Original file line number Diff line number Diff line change
Expand Up @@ -618,26 +618,16 @@ <h2>Ecological Interactions</h2>
<div class="network-tooltip" id="network-tooltip" role="status" aria-live="polite"></div>
<svg id="network-svg" role="img" aria-labelledby="network-svg-title network-svg-desc">
<title id="network-svg-title">Ecological interaction network for Defined Multispecies Enamel Caries Model</title>
<desc id="network-svg-desc">Bipartite graph where circle nodes represent taxa and each ecological interaction is drawn as a distinct non-circular symbol, with colour repeating the same distinction (cross-feeding, competition, colonization facilitation).</desc>
<desc id="network-svg-desc">Bipartite graph where circle nodes represent taxa and each ecological interaction is drawn as a distinct non-circular symbol, with colour repeating the same distinction.</desc>
</svg>
<div class="network-legend">
<div class="legend-item">
<span class="legend-swatch legend-circle" style="background: #7a7a7a;"></span> Taxon
</div>
<div class="legend-item">
<svg class="legend-symbol" width="14" height="14" viewBox="-9 -9 18 18"
aria-hidden="true" data-symbol="symbolDiamond"
data-color="#57c7ab"></svg> Cross-feeding
</div>
<div class="legend-item">
<svg class="legend-symbol" width="14" height="14" viewBox="-9 -9 18 18"
aria-hidden="true" data-symbol="symbolTimes"
data-color="#a91919"></svg> Competition
</div>
<div class="legend-item">
<svg class="legend-symbol" width="14" height="14" viewBox="-9 -9 18 18"
aria-hidden="true" data-symbol="symbolPlus"
data-color="#edab12"></svg> Colonization facilitation
aria-hidden="true" data-symbol="symbolTriangle2"
data-color="#929caa"></svg> Other
</div>
</div>
</div>
Expand All @@ -646,13 +636,24 @@ <h2>Ecological Interactions</h2>
<div class="interaction-card">
<div class="interaction-header">
<h3>Four-Species Enamel Biofilm Formation</h3>
<span class="interaction-type">COLONIZATION_FACILITATION</span>
</div>
<p class="prewrap interaction-description">Lactobacillus casei, Streptococcus mutans, Streptococcus salivarius, and Streptococcus sanguinis formed a defined biofilm on salivary-pellicle-coated enamel slabs during the four-day in vitro caries assay.</p>
<p class="prewrap interaction-description">The four canonical taxa were inoculated onto salivary-pellicle-coated enamel for the four-day assay with daily medium changes. This records the defined starting community and biofilm platform, not demonstrated interspecies colonization facilitation or persistence of all four members in every treatment; S. sanguinis was below detection in the calcium arms.</p>




<p><strong>Participating Taxa:</strong>

Lactobacillus casei,

Streptococcus mutans,

Streptococcus salivarius,

Streptococcus sanguinis

</p>




Expand All @@ -670,21 +671,6 @@ <h3>Four-Species Enamel Biofilm Formation</h3>



<div class="interaction-flow">
<strong>Downstream Effects:</strong>

<div class="flow-item">
<span class="flow-arrow">→</span> Sucrose-Responsive Viable Biofilm Shift
<p class="prewrap causal-description">The established four-species enamel biofilm provided the viable biomass whose cell counts shifted across the sucrose, fluoride, and calcium arms.</p>
</div>

<div class="flow-item">
<span class="flow-arrow">→</span> Mineral-Dependent Demineralization Restraint
<p class="prewrap causal-description">Four days of multispecies biofilm growth on enamel slabs created the demineralization readout modulated by fluoride and calcium.</p>
</div>

</div>



<h4>Evidence</h4>
Expand All @@ -709,13 +695,24 @@ <h4>Evidence</h4>

<div class="interaction-card">
<div class="interaction-header">
<h3>Sucrose-Responsive Viable Biofilm Shift</h3>
<span class="interaction-type">CROSS_FEEDING</span>
<h3>Treatment-Dependent Viable Biofilm Counts</h3>
</div>
<p class="prewrap interaction-description">Changing sucrose in the replacement medium was part of a treatment matrix that significantly altered viable-cell counts in the four-species enamel biofilms.</p>
<p class="prewrap interaction-description">Sucrose, fluoride and calcium treatments altered selected viable-count outcomes in the inoculated model. Higher sucrose increased total counts and L. casei; calcium did not significantly change total counts or S. mutans. Species-specific responses are not a uniform community increase or demonstrated cross-feeding. Acid selection remains a proposed explanation, not a selectively perturbed mechanism.</p>




<p><strong>Participating Taxa:</strong>

Lactobacillus casei,

Streptococcus mutans,

Streptococcus salivarius,

Streptococcus sanguinis

</p>



Expand Down Expand Up @@ -767,13 +764,24 @@ <h4>Evidence</h4>
<div class="interaction-card">
<div class="interaction-header">
<h3>Mineral-Dependent Demineralization Restraint</h3>
<span class="interaction-type">COMPETITION</span>
</div>
<p class="prewrap interaction-description">Higher fluoride and calcium concentrations reduced surface-microhardness change, and 0.8-1.0 ppm fluoride also lowered integrated mineral loss and lesion depth in the enamel slabs.</p>
<p class="prewrap interaction-description">Higher-fluoride arms had lower enamel surface-microhardness change, lesion depth and integrated mineral loss. Calcium at 2 mM reduced surface-microhardness change relative to lower calcium arms, not every mineral-loss endpoint. These are treatment-dependent material outcomes, not microbial competition or proof that altered cell counts mediate protection; proposed calcium/EPS mechanisms were not tested.</p>




<p><strong>Participating Taxa:</strong>

Lactobacillus casei,

Streptococcus mutans,

Streptococcus salivarius,

Streptococcus sanguinis

</p>



<p><strong>Metabolites:</strong>
Expand All @@ -790,17 +798,6 @@ <h3>Mineral-Dependent Demineralization Restraint</h3>



<p><strong>Biological Processes:</strong></p>
<ul>

<li>
biofilm formation
(<a href="http://amigo.geneontology.org/amigo/term/GO:0042710"
class="term-link" target="_blank" rel="noopener noreferrer">GO:0042710</a>)
</li>

</ul>




Expand Down Expand Up @@ -843,6 +840,25 @@ <h4>Evidence</h4>

<!-- Associated Datasets -->

<section id="discussions">
<h2>Knowledge gaps &amp; discussions <span class="muted">(1)</span></h2>

<div class="discussion">
<h3>
<span class="role-badge">KNOWLEDGE_GAP</span>
<span class="role-badge">OPEN</span>
Which microbial processes mediate the observed treatment-dependent counts and enamel outcomes?
</h3>
<p class="prewrap">The primary paper and Tables 1-2 support positive experimental outcomes but not cross-feeding, reciprocal competition, calcium/EPS mediation or selective pH causality. Distinguish starting roster from recoverable members. The Results prose and Table 2 superscripts differ on one L. casei calcium comparison; no disputed 1-versus-2 mM claim is used here. The two removed arrows described assay context, not mechanistic mediation. Non-graph follow-up: #1380.</p>

<p class="muted small">Attaches to: <code>ecological_interactions#Four-Species Enamel Biofilm Formation</code>, <code>ecological_interactions#Treatment-Dependent Viable Biofilm Counts</code>, <code>ecological_interactions#Mineral-Dependent Demineralization Restraint</code></p>




</div>

</section>

<!-- Environmental Factors -->

Expand Down Expand Up @@ -1112,7 +1128,7 @@ <h4 style="color: var(--text);">Evidence</h4>

(function() {
var intId = "interaction:0";
var intType = "COLONIZATION_FACILITATION";
var intType = "UNKNOWN";
var metabolites = [];

var processes = [];
Expand All @@ -1136,11 +1152,28 @@ <h4 style="color: var(--text);">Evidence</h4>



var participantKeys = [

"Lactobacillus casei",

"Streptococcus mutans",

"Streptococcus salivarius",

"Streptococcus sanguinis"

];
participantKeys.forEach(function(key) {
if (taxonNodeIds[key]) {
links.push({ source: taxonNodeIds[key], target: intId });
}
});

})();

(function() {
var intId = "interaction:1";
var intType = "CROSS_FEEDING";
var intType = "UNKNOWN";
var metabolites = [];


Expand All @@ -1157,7 +1190,7 @@ <h4 style="color: var(--text);">Evidence</h4>

nodes.push({
id: intId,
label: "Sucrose-Responsive Viable Biofilm Shift",
label: "Treatment-Dependent Viable Biofilm Counts",
type: "interaction",
interactionType: intType,
metabolites: metabolites,
Expand All @@ -1168,11 +1201,28 @@ <h4 style="color: var(--text);">Evidence</h4>



var participantKeys = [

"Lactobacillus casei",

"Streptococcus mutans",

"Streptococcus salivarius",

"Streptococcus sanguinis"

];
participantKeys.forEach(function(key) {
if (taxonNodeIds[key]) {
links.push({ source: taxonNodeIds[key], target: intId });
}
});

})();

(function() {
var intId = "interaction:2";
var intType = "COMPETITION";
var intType = "UNKNOWN";
var metabolites = [];


Expand All @@ -1183,10 +1233,6 @@ <h4 style="color: var(--text);">Evidence</h4>

var processes = [];


processes.push("biofilm formation");


var evidenceCount = 2;

nodes.push({
Expand All @@ -1202,6 +1248,23 @@ <h4 style="color: var(--text);">Evidence</h4>



var participantKeys = [

"Lactobacillus casei",

"Streptococcus mutans",

"Streptococcus salivarius",

"Streptococcus sanguinis"

];
participantKeys.forEach(function(key) {
if (taxonNodeIds[key]) {
links.push({ source: taxonNodeIds[key], target: intId });
}
});

})();


Expand Down
Original file line number Diff line number Diff line change
@@ -0,0 +1,31 @@
history_version: 1
target:
kind: record
path: kb/communities/Dangl_SynComm_35.yaml
slug: Dangl_SynComm_35
session:
id: 2026-10-06T052450Z-codex-4c42b0
timestamp: '2026-10-06T05:24:50Z'
actors:
- type: ai_agent
name: codex
model: unspecified
agent_tool: codex
links:
issues:
- https://github.com/CultureBotAI/CommunityMech/issues/1375
events:
- type: EDIT
outcome: changed
sections:
- interactions
- discussions
summary: Retain positive root immune suppression at community scope; do not assign community
readouts exclusively to MF79.; Retain the primary-body WRKY observation without converting
proposed regulatory/homeostasis roles into proven causality; abstract snippet support
is explicitly partial.; Retain the tested MF79 secretion-system mechanism and existing
arrow with strain-specific scope and unresolved effector identity.; Retain experimentally
supported colonization facilitation, distinguish assay contexts and incomplete canonical
participants, and remove reciprocal-fitness attribution.
details: Primary-source self-adversarial repair, qualification and removal; no new nodes
or arrows. reports/causal_graph_review/decisions/20261006-three-records-batch29.yaml
Original file line number Diff line number Diff line change
@@ -0,0 +1,30 @@
history_version: 1
target:
kind: record
path: kb/communities/Deepwater_Horizon_Deep_Sea_Oil_Plume_Succession.yaml
slug: Deepwater_Horizon_Deep_Sea_Oil_Plume_Succession
session:
id: 2026-10-06T052450Z-codex-df845f
timestamp: '2026-10-06T05:24:50Z'
actors:
- type: ai_agent
name: codex
model: unspecified
agent_tool: codex
links:
issues:
- https://github.com/CultureBotAI/CommunityMech/issues/1376
events:
- type: EDIT
outcome: changed
sections:
- interactions
- discussions
summary: Retain measured cold biodegradation and qualified bioremediation potential; consolidate
duplicate oxygen context without asserting syntrophy or oxygen conservation.; Retain positive
Colwellia-dominated flocs while qualifying their proposed contribution to degradation
and removing unsupported facilitation.; Retain positive SIP/genome evidence and the complementary-pathway
hypothesis, distinguish surface/deep and laboratory/field contexts, and retain alternative
explanations.
details: Primary-source self-adversarial repair, qualification and removal; no new nodes
or arrows. reports/causal_graph_review/decisions/20261006-three-records-batch29.yaml
Original file line number Diff line number Diff line change
@@ -0,0 +1,28 @@
history_version: 1
target:
kind: record
path: kb/communities/Defined_Multispecies_Enamel_Caries_Model.yaml
slug: Defined_Multispecies_Enamel_Caries_Model
session:
id: 2026-10-06T052450Z-codex-bf5211
timestamp: '2026-10-06T05:24:50Z'
actors:
- type: ai_agent
name: codex
model: unspecified
agent_tool: codex
links:
issues:
- https://github.com/CultureBotAI/CommunityMech/issues/1377
events:
- type: EDIT
outcome: changed
sections:
- interactions
- discussions
summary: Retain the inoculated biofilm platform without interspecies facilitation or universal
persistence claims.; Retain treatment- and species-specific viable-count outcomes without
cross-feeding or a uniform calcium effect.; Retain endpoint-specific enamel mineral outcomes
without microbial competition or an untested mediation mechanism.
details: Primary-source self-adversarial repair, qualification and removal; no new nodes
or arrows. reports/causal_graph_review/decisions/20261006-three-records-batch29.yaml
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